From 2000 to 2006, he worked in the Makeyevka Directorate for Combating Organized Crime in the Donetsk Region. He was engaged in preventing the facts of illegal circulation of goods and material values in Ukraine.
Later he worked in the Makiivka Department of Internal Security of the Ministry of Internal Affairs of Ukraine until 2012, after which he worked for a year and a half as head of the city police department of the Gornitsa department in Makiivka.
On 12.06.2013, order №3/169 Doroshenko Yuri Pavlovich was sent to other units of the Ministry of Internal Affairs for further service.
In 2014, during the beginning of the Russian aggression, he refused to comply with an order from the top leadership to relocate the Main Directorate of the Interior Ministry of Ukraine in Donetsk Region to the Ukrainian-controlled city of Mariupol, after which he began cooperating with the occupant.
After the beginning of large-scale Russian aggression in February 2022, Yuri Pavlovich was appointed to the position of the so-called Director of the State Service for the Execution of Punishments of the Ministry of Justice of the “DPR.